Job Information
Merck Postdoctoral Research Fellow - Stem Cell Models for Neuroimmunology- Oligodendrocyte Research in Cambridge, Massachusetts
Job Description
Be a part of the legacy: Postdoctoral Research Fellow Program
Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
Postdoctoral Fellow in Oligodendrocyte Research
We are seeking a highly motivated and talented individual to join our research team as a Postdoctoral Fellow in Oligodendrocyte Research. The successful candidate will establish a research program that is focused on understanding mechanisms underlying oligodendrocyte lineage cells growth, differentiation, maintenance, and remyelination potential in the central nervous system (CNS). The successful candidate will have the unique opportunity to contribute to the development of therapeutic candidates targeting oligodendrocyte-lineage cell function enhancement during neurodegenerative diseases.
Responsibilities:
Conduct experimental research to investigate the growth, differentiation, and metabolic support of OPCs, as well as their myelination potential in the developing CNS (central nervous system).
Utilize single-cell RNA sequencing (scRNAseq) and spatial transcriptomics data from iPSCs-derived translational models to identify disease-associated oligodendrocytes (DOLs) markers.
Develop and maintain long-term in vitro models of OPCs differentiation from human pluripotent stem cells (iPSCs) that mimic in vivo conditions.
Collaborate with a multidisciplinary team to design and execute experiments.
Analyze and interpret data and contributing to scientific publications and presentations.
Present research findings at conferences and scientific meetings.
Minimum education required:
- Ph.D. in a relevant field such as stem cell biology, neurobiology, or a related discipline expected by May 1, 2025.
Required experience skills:
Strong background in cell culture techniques, iPSC differentiation, and molecular biology.
Experience with single-cell RNA sequencing and bioinformatics analysis is highly desirable.
Experience in CNS or neurology or related field.
Demonstrated skills in experimental design, data analysis, and interpretation.
Excellent written and oral communication skills.
Ability to work independently and collaboratively in a team setting.
Track record of scientific publications is advantageous.
We offer:
A stimulating and supportive research environment with state-of-the-art facilities
Access to a multidisciplinary team comprised of experienced researchers and machine learning engineers.
Opportunities for career development, mentorship, and training.
Competitive salary and benefits package.
Application: Applicants should submit a cover letter outlining their research experience and interests, a detailed curriculum vitae (CV), a list of publications, and contact information for three references.
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Employee Status:
Regular
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Job Posting End Date:
11/15/2024
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Requisition ID: R316450
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