Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents. We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

The Functional Assays team within Discovery Biotherapeutics plays a key role in characterizing molecules to enable the discovery of first in class and/or best in class biotherapeutics. The Scientist position is in Cambridge, MA, working with cross-functional matrixed teams across other BMS sites. The position entails the utilization of broad in vitro biochemical and cellular techniques to accelerate primary antibody screen workflow execution and downstream mechanistic characterization of a wide range of biotherapeutic drug candidates, including antibody drug conjugates, bispecific and multi-specific antibodies, and other formats. Expertise in designing and executing validating primary screening assays and downstream functional assays for hit selection and characterization of leads will be vital too the discovery of efficacious biologics candidates build a full characterization of lead biologic candidates. The successful candidate is expected to be self-motivated, energetic, and detail oriented. The candidate should be able to thrive in a highly dynamic, supportive, yet independently thinking culture.

Key Responsibilities

• Develop fit-for-purpose primary screening assays and provide characterization support for lead molecules

• Explore commercial sources or design and execute cellular assays for functional characterization including signaling, internalization, and cytotoxicity readouts

• Characterize protein reagents using techniques including flow cytometry, biolayer interferometry, and homogeneous biochemical assays

• Serve as functional assay representative on matrixed multidisciplinary project teams

• Analyze and present data to stakeholders

• Document experiments meticulously in Electronic Notebook

Basic Qualifications:

Bachelor's Degree with 5+ years of academic or industry experience

Or

Master's Degree with 3+ years of academic or industry experience

Or

PhD and no years of experience

Preferred Qualifications

• In-depth knowledge and hands-on experience in various techniques for protein and antibody characterization

• Experience with developing engineered cell lines for binding and functional screening assays

• PhD in a relevant discipline

• Experience with lentiviral transduction/CRISPR

• Experience with cell culture

• Experience with flow cytometry, or cell imaging and other cellular assay techniques

• Proficiency in programming skills to enable automation processes such as high-throughput liquid handling

• Proficiency with database management/entry (such as Genedata or LIMS)Experience with cell culture

• Proficiency with data visualization using Spotfire

• Proficiency with DOE and JMP

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Company: Bristol-Myers Squibb

Req Number: R1583259

Updated: 2024-07-08 04:15:23.186 UTC

Location: Cambridge Crossing-MA

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.